Introduction to AlphaFold

Content

AlphaFold is a groundbreaking machine learning tool in the complex field of protein folding. Simple to use, but hard to master and understand, AlphaFold provides a vital step in many bioinformatics and molecular simulation workflows. In this tutorial, we will cover the theoretical background of AlphaFold, show examples of incorporating it into a research workflow, provide an opportunity to perform hands-on AlphaFold simulations, and explore advanced techniques and alternative algorithms.

Requirements

• Knowledge of HPC usage in general, working with a terminal
• Background knowledge of basic biological concepts (DNA, proteins, protein synthesis, etc)
• Not necessary/will be covered, but nice to have: AI/ML, molecular simulations, GPUs

Learning goal

• Basics of protein folding with AlphaFold
• Incorporating AlphaFold into your workflow
• Hands on folding and simulation experience

Skills

Trainer

• Dr. Martin Leandro Paleico
• Dr. Narges Lux

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